The physiologic heart is a muscular powerful pump that twitches with rhythm and pushes her content, the blood, to the circulation. Diseases that influence the good operation of heart are diseases of myocardium and cardiomyopathies. Moreover the two more frequent types of cardiomyopathy are the hypertrophy and the dilated cardiomyopathy or differently the congestive cardiomyopathy. The patients with dilated cardiomyopathy require continuous follow-up and pharmaceutical treatment. The patients that will not have marks of improvement despite the pharmaceutical treatment and their situation is overloaded will need to be submitted in cardiac transplantation. The prognosis of dilated cardiomyopathy was particular adverse while today, the early recognition of illness increases the rate of survival. Recently, has been made a huge progress in identifying genetic causes for each cardiomyopathy.