Education helps patients with renal failure to increase their knowledge about their condition and effectively manage their treatment. Additionally, psychological support helps patients to overcome all problems caused by their condition and adapt effectively to their new way of life. The main purpose of education should be the physical, mental and social rehabilitation of people with renal failure. Also, the appropriate psychological support helps these patients to accept their condition with maturity. Nurses play a key role in education and psychological support of patients with renal failure. Finally, education is necessary to be carried out before and after the initiation of renal replacement therapy.