Diabetes mellitus Type II, (non-insulin-dependent) consists one of the greatest problems that the individual has faced, globally. The number of patients is increasing dramatically every year and is expected to be double the next decades. The aetiology and pathogenesis of the disease is mainly attributed to genetic factors. The aim of present study was to evaluate whether administration of an educational program can contribute to the control of the disease. The method οf this study included bibliography research from both the review and the research literature which referred to the relationship between education and the control of diabetes mellitus, type II. Results: The majority of research studies showed that there is a very strong correlation between education and the maintenance of plasma glucose level of patients with diabetes mellitus, type II, within normal range. An effective educative program is mainly comprised of basic knowledge of these parameters that exert a beneficial effect on the management of the disease such as : healthy nutrition habits, participation in physical exercise programs, avoidance of sedentary life, self-monitoring of glucose, correct way to perform insulin injections, etc. The overall goal of the educative intervention is to help individuals with diabetes gain the necessary knowledge and support needed, to achieve optimal health by modifying their behaviour and adopting a more positive attitude to the disease. Conclusions: The present review confirms that educational intervention has beneficial effects on the control of Type II Diabetes Mellitus. The maintenance of plasma glucose levels into normal range indicates the effectiveness of education.