During recent years, it has been noticed a remarkable increase in frequency of admission of young individuals in Intensive Care Units (ICU) due to road accidents. The aim of the present study was to compare the reasons of admission of young individuals 18-30 years old to young adults 31-40 years old in ICU due to road accident. Method and material: The sample studied consisted of individuals 18-40 years old that were hospitalized in ICU due to road accident. Data were collected by the completion of a specially designed clinical protocol for the needs of the research. For the analysis of data the statistical package SPSS 13 was used and the x2 method. Results: 81,2% of the sample-studied were men and 18,8% women. Regarding nationality, 80,1 % were Greek and 19,9% foreigner. 34,6% of the participants were unemployed, 21,2% were working in private sector, 20,1% were free-lancers and 16,2% students. 46,3% of individuals were admitted in ICU after transfer of another hospital. In 69,7% of the participants age 18-30 years old and 74,5% of 31-40 years old road took place accident at night and 77,3% 18-30 years old and 77,0% of 31-40 years old road accident took place on the way to entertainment. The statistical analysis of data showed that : road accidents were the main reason for admission in ICU of young individuals of age 18-30 years old with statistically significant difference compared to those 31-40 years old, p<0,001. Brain injuries as well as admission of motorcycle drivers were more frequent in individuals of age 18-30 years old with statistically significant difference compared to those 31-40 years old, p=0,018 and p=0,041, respectively. On the contrary, admission of car-drivers and those who had consumed alcohol were more frequent in individuals of age 31-40 years old with statistically significant difference compared to group 18-30 years old, p=0,041 and , p<0,001, respectively. Conclusions: More often admitted in ICU motorcycle drivers of age 18-30 years old, whereas of the group age 31-40 years the car-drivers and those that had consumed alcohol. Furthermore, the results of the present study highlight the importance of ICU in every hospital.