The Asperger’s Syndrome is reported in the pervasive developmental disorders and was categorized as a separate disorder, initially in the ICD‐10 (World Health Organization, 1992) and afterwards in the DSM‐IV (American Psychiatric Organization, 1994). The Asperger’s Syndrome is distinguished by a team of symptoms that concern the low output in the social interaction and the communication dexterities, as well as the increased stereotypical behavior in various activities and interests. Aim: The aim of this present study was the descriptive review of bibliography concerning the epidemiology, the differential diagnosis from the autism, the etiology, the diagnosis, the therapeutic approaches and the adaptation difficulty of the family environment, with regard to the investigation of the Asperger ’s syndrome. Material and method: In the present review, the methodology that was followed included specialized electronic research with regard to the Asperger’s syndrome in children, using special keywords. Results: The review of the bibliography showed that the individuals with Asperger’s syndrome experience really big difficulties in elementary social behaviors, as failure in the growth and creation of friendly relations or in the search of amusing activities with others. Also, they face difficulties in the comprehension of not verbal communication (body language) and the other’s expressions, the attitudes of body and the eye contact. Conclusions: The precocious recognition of Asperger’ s syndrome is imperative, with final objective the continuous briefing and sensitization of all health professionals as well as the wider public toward this, under the prism of interdisciplinary approach.